Volume 12, Number 1, January 2006
Cell-mediated Protection in Influenza Infection
Paul G. Thomas,* Rachael Keating,* Diane J. Hulse-Post,* and Peter
C. Doherty*
*St. Jude Children's Research Hospital, Memphis, Tennessee, USA
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Figure. Apparent cell-mediated protection against highly pathogenic H5N1 influenza virus. Mice (10 in each group) were immunized by intraperitoneal injection of PR8, followed by intraperitoneal injection 4 weeks later of X31. Four weeks after the second immunization, immunized or naive mice were infected with 300 mouse lethal dose 50% of A/Vietnam/1203/2004. |
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