Volume 12, Number 1, January 2006
Estimating Influenza Hospitalizations among Children
Carlos G. Grijalva,* Allen S. Craig,*† William D. Dupont,* Carolyn
B. Bridges,‡ Stephanie J. Schrag,‡ Marika K. Iwane,‡ William Schaffner,*
Kathryn M. Edwards,* and Marie R. Griffin*
*Vanderbilt University School of Medicine; Nashville, Tennessee, USA;
†Tennessee Department of Health, Nashville, Tennessee, USA; and ‡Centers
for Disease Control and Prevention, Atlanta, Georgia, USA
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Figure 1. Capture-recapture estimation using data from 2 independent
sources. The first surveillance system (New Vaccine Surveillance Network
[NVSN]) captured n1 cases. The second system (Emerging Infections Program
[EIP]) captured n2 cases, including m2 cases already captured by NVSN
(matched cases). The Peterson estimator of N (total cases) is
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=
n1 × n2/m2. The Peterson estimate implies that the estimated number
of cases missed by both systems (z) = (b × c)/(a); where b is the
number of enrolled cases by the EIP only, c is the number of enrolled
cases by the NVSN only, and a is the number of matched cases (m2) (